ncRNA name | VEGF siRNA |
ncRNA Category | siRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | human RB cell lines SO-RB50 and HXO-RB44 |
Methods | siRNA transfection, qPCR, Western blot, ELISA |
Expression pattern | associated |
Functional description | The chemically synthesized VEGF siRNA dramatically suppressed tumor angiogenesis (CD34 immunohistochemistry) and tumor growth in the SO-RB50 subcutaneous xenograft model. |
PubMed ID | 17284938 |
Year | 2007 |
Title | VEGF-targeted RNA interference suppresses angiogenesis and tumor growth of retinoblastoma. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.